Archive for the ‘skin cancer’ Category

Robust experimental evidence supporting many attempts to facilitate early melanoma diagnosis is lacking. In an experimental study using a browser interface we have examined diagnostic accuracy, sensitivity and specificity of novices in distinguishing between melanomas and mimics of melanoma. We show that rule-based ABC methods and image training, based on random images of melanoma, improve […]

Well, who says there isn’t enough quantification in biology and medicine. The quotes below are from ‘The Southern Star’, a journal not to be missed if you want to move in fashionable circles in West Cork (sent by my sister in law, Sue, who lives in a Welsh castle close to Castletownsend). Most freckles per […]

My letter in the BMJ is here. Sadly they sanitised my rapid response (here) which ended saying: Finally, the simplest explanation for the persistence of SLN — in the absence of convincing RCT support— is surely that given by people such as John Wennberg in explaining variation in health care provision: money — or at […]

Much biomedical research bores me. All too often it is either dull risk factorology (i.e. most epidemiology) or, as for so much cell biology and biochemistry, endless chasing of one molecule causing another molecule to change and, in turn, alter yet another molecule. The cascade goes on: there are lots of molecules after all. It […]

The current management of skin cancer in the UK and many countries is based on what might be termed a ‘corner shop’ model. Patients present to their general practitioner (GP) or to a single- handed dermatologist in office practice and either (i) are diagnosed as not needing further treatment because the suspect lesion is benign, […]

Here is a link to our DERMOFIT publications but I can control more of the links below. We still have some papers to do with learning either under  consideration or yet to write (Ben get on with it!) The publications produced by DERMOFIT or linked projects are: L. Ballerini et al, A color and texture […]

There is a debate — like for many cancers — about whether much or all of the increase in melanoma rates reflects increases in ‘real melanomas’ or changes in diagnostic habits. I do not think the evidence is robust enough to decide absolutely. I wrote something in the BMJ many years ago on this topic […]

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